In 2019, Christopher Germann published the Psilocybin-Telomere Hypothesis, a bold, falsifiable prediction that psilocybin should measurably slow genetic aging by preserving telomere length (Germann, Medical Hypotheses, 2020). He built the case from psilocybin's durable mental health benefits and the known link between wellbeing and longer telomeres. Six years later, Hecker and colleagues at Emory tested it directly (Kato et al., npj Aging, 2025). In human fibroblasts, psilo

I cannot stop thinking about this study. Psilocybin's metabolite, psilocin, extended human cell lifespan by up to 57% in lab conditions, preserved telomere length, and lowered oxidative stress.In aged mice (early 60s in human years), 80% survived a 10 month course, versus 50% untreated, with bald patches regrowing fur and grey turning brown again. This is early evidence (cells in dishes, then mice, not yet humans). But it points somewhere bigger than "psychedelics help depres

Functional mushrooms have been used for centuries in Traditional Chinese Medicine and Indigenous healing practices to support vitality, immunity, cognition, and overall well-being. Today, modern research is beginning to explore how certain mushrooms may support the nervous system, immune function, stress resilience, and mental health. Popular functional mushrooms include: Reishi — traditionally associated with relaxation, immunity, and stress support Lion’s Mane — researched

A new study published in the journal European Psychiatry has shed light on an unconventional approach to managing symptoms associated with Attention-Deficit Hyperactivity Disorder (ADHD). The findings suggest that small, repeated doses of substances like psilocybin and lysergic acid diethylamide (LSD) could potentially help reduce ADHD symptoms and enhance some aspects of emotion regulation. These findings could pave the way for new treatments that focus not only on the prima

Alzheimer’s disease (AD) stands as a formidable neurodegenerative ailment and a prominent contributor to dementia. The scarcity of available therapies for AD accentuates the exigency for innovative treatment modalities. Psilocybin, a psychoactive alkaloid intrinsic to hallucinogenic mushrooms, has garnered attention within the neuropsychiatric realm due to its established safety and efficacy in treating depression. Nonetheless, its potential as a therapeutic avenue for AD rem

People have used psychedelics to commune with the divine and create bonds among the living and the dead, the spiritual and the natural worlds for centuries and possibly millennia. Pre-Incan civilizations consumed the San Pedro cactus, which contains mescaline; Vedic and Zoroastrian traditions consumed soma, which some scholars believe may have been based on mushrooms containing psychoactive ingredients; Bantu diviners use psychedelic herbs called ubulawu during healing ceremo

In a small study of adults with major depression, Johns Hopkins Medicine researchers report that two doses of the psychedelic substance...

Have you ever wondered what goes on inside your brain during a psychedelic trip? The mysteries of psilocybin, the primary psychoactive...